Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology

Zika virus (ZIKV) infection during pregnancy leads to an increased risk of fetal growth restriction and fetal central nervous system malformations, which are outcomes broadly referred to as the Congenital Zika Syndrome (CZS). Here we infect pregnant rhesus macaques and investigate the impact of pers...

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Publicado no:Nat Commun
Main Authors: Hirsch, Alec J., Roberts, Victoria H. J., Grigsby, Peta L., Haese, Nicole, Schabel, Matthias C., Wang, Xiaojie, Lo, Jamie O., Liu, Zheng, Kroenke, Christopher D., Smith, Jessica L., Kelleher, Meredith, Broeckel, Rebecca, Kreklywich, Craig N., Parkins, Christopher J., Denton, Michael, Smith, Patricia, DeFilippis, Victor, Messer, William, Nelson, Jay A., Hennebold, Jon D., Grafe, Marjorie, Colgin, Lois, Lewis, Anne, Ducore, Rebecca, Swanson, Tonya, Legasse, Alfred W., Axthelm, Michael K., MacAllister, Rhonda, Moses, Ashlee V., Morgan, Terry K., Frias, Antonio E., Streblow, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772047/
https://ncbi.nlm.nih.gov/pubmed/29343712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02499-9
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