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Reduced serum IGF-1 associated with hepatic osteodystrophy is a main determinant of low cortical but not trabecular bone mass

Hepatic osteodystrophy is multifactorial in its pathogenesis. Numerous studies have shown that impairments of the hepatic growth hormone/insulin-like growth factor-1 axis (GH/IGF-1) are common in patients with non-alcoholic fatty liver disease, chronic viral hepatitis, liver cirrhosis, and chronic c...

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Détails bibliographiques
Publié dans:J Bone Miner Res
Auteurs principaux: Liu, Zhongbo, Han, Tianzhen, Werner, Haim, Rosen, Clifford J, Schaffler, Mitchell B, Yakar, Shoshana
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771972/
https://ncbi.nlm.nih.gov/pubmed/28902430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3290
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