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Site-specific glycan heterogeneity characterization by HILIC solid-phase extraction, RPLC fractionation, and capillary zone electrophoresis-electrospray ionization-tandem mass spectrometry
Reversed-phase chromatographic separation of glycopeptides tends to be dominated by the peptide composition. In contrast, capillary zone electrophoresis separation of glycopeptides is particularly sensitive to the sialic acid composition of the glycan. In this paper, we combine the two techniques to...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771954/ https://ncbi.nlm.nih.gov/pubmed/29231704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b03912 |
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