Pharmacokinetics and safety profile of single-dose administration of an estrogen receptor β-selective phytoestrogenic (phytoSERM) formulation in peri- and postmenopausal women

BACKGROUND: PhytoSERM, a preparation of genistein, daidzein, and S-equol, has an 83-fold selective affinity for estrogen receptor (ER) β and may promote neuronal survival and estrogenic mechanisms in the brain without exerting feminizing activity in the periphery. OBJECTIVE: To assess the safety, to...

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Veröffentlicht in:Menopause
Hauptverfasser: Hernandez, Gerson, Zhao, Liqin, Franke, Adrian A., Chen, Yu-Ling, Mack, Wendy J., Brinton, Roberta D., Schneider, Lon S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771891/
https://ncbi.nlm.nih.gov/pubmed/28926513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0000000000000984
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