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Thiopurine-induced mitotic catastrophe in Rad51d-deficient mammalian cells

Thiopurines are part of a clinical regimen used for the treatment of autoimmune disorders and childhood acute lymphoblastic leukemia. However, despite these successes, there are also unintended consequences such as therapy-induced cancer in long-term survivors. Therefore, a better understanding of c...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Wyatt, Michael D., Reilly, Nicole M., Patel, Shikha, Rajesh, Preeti, Schools, Gary P., Smiraldo, Phillip G., Pittman, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771848/
https://ncbi.nlm.nih.gov/pubmed/28945288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22138
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