Vimentin is required for lung adenocarcinoma metastasis via heterotypic tumor cell-cancer-associated fibroblast interactions during collective invasion

PURPOSE: Vimentin is an epithelial to mesenchymal transition (EMT) biomarker and intermediate filament protein that functions during cell migration to maintain structure and motility. Despite the abundance of clinical data linking vimentin to poor patient outcome, it is unclear if vimentin is requir...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Richardson, Alessandra M., Havel, Lauren S., Koyen, Allyson E., Konen, Jessica M., Shupe, John, Wiles, W. G, Martin, W. David, Grossniklaus, Hans E., Sica, Gabriel, Gilbert-Ross, Melissa, Marcus, Adam I.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771825/
https://ncbi.nlm.nih.gov/pubmed/29208669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1776
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