A Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria

We report a mitochondria-specific glutathione (GSH) probe—designated as Mito-RealThiol (MitoRT)—that can monitor in vivo real-time mitochondrial glutathione dynamics, and apply this probe to follow mitochondrial GSH dynamic changes in living cells for the first time. MitoRT can be utilized in confoc...

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Udgivet i:ACS Sens
Main Authors: Chen, Jianwei, Jiang, Xiqian, Zhang, Chengwei, MacKenzie, Kevin R., Stossi, Fabio, Palzkill, Timothy, Wang, Meng C., Wang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771714/
https://ncbi.nlm.nih.gov/pubmed/28809477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.7b00425
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