Mixed Neurodevelopmental and Neurodegenerative Pathology in Nhe6-Null Mouse Model of Christianson Syndrome

Christianson syndrome (CS) is an X-linked disorder resulting from loss-of-function mutations in SLC9A6, which encodes the endosomal Na(+)/H(+) exchanger 6 (NHE6). Symptoms include early developmental delay, seizures, intellectual disability, nonverbal status, autistic features, postnatal microcephal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eNeuro
Prif Awduron: Xu, Meiyu, Ouyang, Qing, Gong, Jingyi, Pescosolido, Matthew F., Pruett, Brandon S., Mishra, Sasmita, Schmidt, Michael, Jones, Richard N., Gamsiz Uzun, Ece D., Lizarraga, Sofia B., Morrow, Eric M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2018
Pynciau:
New Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771691/
https://ncbi.nlm.nih.gov/pubmed/29349289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0388-17.2017
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