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RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis

Bone destruction occurs in aging and numerous diseases, including osteoporosis and cancer. Many cancer patients have bone osteolysis that is refractory to state-of-the-art treatments, which block osteoclast activity with bisphosphonates or by inhibiting the RANKL pathway. We previously showed that m...

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Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Andrade, Kelsi, Fornetti, Jaime, Zhao, Ling, Miller, Scott C., Randall, R. Lor, Anderson, Neysi, Waltz, Susan E., McHale, Mark, Welm, Alana L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771677/
https://ncbi.nlm.nih.gov/pubmed/28123075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aai9338
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