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Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow

Low and disturbed blood flow drives the progression of arterial diseases including atherosclerosis and aneurysms. The endothelial response to flow and its interactions with recruited platelets and leukocytes determine disease progression. Here, we report widespread changes in alternative splicing of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Murphy, Patrick A, Butty, Vincent L, Boutz, Paul L, Begum, Shahinoor, Kimble, Amy L, Sharp, Phillip A, Burge, Christopher B, Hynes, Richard O
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771670/
https://ncbi.nlm.nih.gov/pubmed/29293084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29494
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