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Silymarin prevents acetaminophen-induced hepatotoxicity in mice

Acetaminophen or paracetamol (APAP) overdose is a common cause of liver injury. Silymarin (SLM) is a hepatoprotective agent widely used for treating liver injury of different origin. In order to evaluate the possible beneficial effects of SLM, Balb/c mice were pretreated with SLM (100 mg/kg b.wt. pe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Papackova, Zuzana, Heczkova, Marie, Dankova, Helena, Sticova, Eva, Lodererova, Alena, Bartonova, Lenka, Poruba, Martin, Cahova, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771617/
https://ncbi.nlm.nih.gov/pubmed/29342206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191353
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