Induction of high tolerance to artemisinin by sub-lethal administration: A new in vitro model of P. falciparum

Artemisinin resistance is a major threat to malaria control efforts. Resistance is characterized by an increase in the Plasmodium falciparum parasite clearance half-life following treatment with artemisinin-based combination therapies (ACTs) and an increase in the percentage of surviving parasites....

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Bibliographic Details
Published in:PLoS One
Main Authors: De Lucia, Serena, Tsamesidis, Ioannis, Pau, Maria Carmina, Kesely, Kristina R., Pantaleo, Antonella, Turrini, Francesco
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771598/
https://ncbi.nlm.nih.gov/pubmed/29342187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191084
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