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Inhibition of an Erythrocyte Tyrosine Kinase with Imatinib Prevents Plasmodium falciparum Egress and Terminates Parasitemia

With half of the world’s population at risk for malaria infection and with drug resistance on the rise, the search for mutation-resistant therapies has intensified. We report here a therapy for Plasmodium falciparum malaria that acts by inhibiting the phosphorylation of erythrocyte membrane band 3 b...

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Publicado en:PLoS One
Autores principales: Kesely, Kristina R., Pantaleo, Antonella, Turrini, Francesco M., Olupot-Olupot, Peter, Low, Philip S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074466/
https://ncbi.nlm.nih.gov/pubmed/27768734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164895
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