Nanoscopic X-ray fluorescence imaging and quantification of intracellular key-elements in cryofrozen Friedreich’s ataxia fibroblasts

Synchrotron radiation based nanoscopic X-ray fluorescence (SR nano-XRF) analysis can visualize trace level elemental distribution in a fully quantitative manner within single cells. However, in-air XRF analysis requires chemical fixation modifying the cell’s chemical composition. Here, we describe f...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: De Samber, Björn, Meul, Eline, Laforce, Brecht, De Paepe, Boel, Smet, Joél, De Bruyne, Michiel, De Rycke, Riet, Bohic, Sylvain, Cloetens, Peter, Van Coster, Rudy, Vandenabeele, Peter, Vanden Berghe, Tom
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771581/
https://ncbi.nlm.nih.gov/pubmed/29342155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190495
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