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A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions

ABC multidrug transporters are key players in cancer multidrug resistance and in general xenobiotic elimination, thus their functional assays provide important tools for research and diagnostic applications. In this study we have examined the potential interactions of three key human ABC multidrug t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Szabó, Edit, Türk, Dóra, Telbisz, Ágnes, Kucsma, Nóra, Horváth, Tamás, Szakács, Gergely, Homolya, László, Sarkadi, Balázs, Várady, György
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771559/
https://ncbi.nlm.nih.gov/pubmed/29342177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190629
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