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Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje cell-Dependent Ventricular Arrhythmias
BACKGROUND: In human cardiac ventricle, I(K1) is mainly comprised of Kir2.1, but Kir2.2 and Kir2.3 heterotetramers occur and modulate I(K1.) LQT9-associated CAV3 mutations cause decreased Kir2.1 current density, but Kir2.x heterotetramers have not been studied. Here we determine the effect of LQT9-C...
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| Publicado en: | Circ Arrhythm Electrophysiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771420/ https://ncbi.nlm.nih.gov/pubmed/29326130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.117.005800 |
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