The Interaction of Caveolin 3 Protein with the Potassium Inward Rectifier Channel Kir2.1: PHYSIOLOGY AND PATHOLOGY RELATED TO LONG QT SYNDROME 9 (LQT9)

Mutations in CAV3 cause LQT syndrome 9 (LQT9). A previously reported LQT9 patient had prominent U waves on ECG, a feature that has been correlated with Kir2.1 loss of function. Our objective was to determine whether caveolin 3 (Cav3) associates with Kir2.1 and whether LQT9-associated CAV3 mutations...

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Detalhes bibliográficos
Main Authors: Vaidyanathan, Ravi, Vega, Amanda L., Song, Chunhua, Zhou, Qing, Tan, Bihua, Berger, Stuart, Makielski, Jonathan C., Eckhardt, Lee L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682547/
https://ncbi.nlm.nih.gov/pubmed/23640888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.435370
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