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The ubiquitin-specific protease USP36 is a conserved histone H2B deubiquitinase
Histone H2B monoubiquitination plays a critical role in the regulation of gene transcription. Deregulation of H2B monoubiquitination contributes to human pathologies, such as cancer. Here we report that human USP36 is a novel H2Bub1 deubiquitinase. We show that USP36 interacts with H2B and deubiquit...
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| Veröffentlicht in: | Biochem Biophys Res Commun |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771408/ https://ncbi.nlm.nih.gov/pubmed/29274341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.12.107 |
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