In Vivo Double Targeting of C26 Colon Carcinoma Cells and Microenvironmental Protumor Processes Using Liposomal Simvastatin

Purpose: Besides cholesterol lowering effects, simvastatin (SIM) at very high doses possesses antitumor actions. Moreover our previous studies demonstrated that tumor-targeted delivery of SIM by using long-circulating liposomes (LCL) improved the therapeutic index of this drug in murine melanoma-bea...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Luput, Lavinia, Licarete, Emilia, Drotar, Denise Minerva, Nagy, Andras-Laszlo, Sesarman, Alina, Patras, Laura, Rauca, Valentin Florian, Porfire, Alina, Muntean, Dana, Achim, Marcela, Tomuta, Ioan, Vlase, Laurian, Catoi, Cornel, Dragos, Nicolae, Banciu, Manuela
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771352/
https://ncbi.nlm.nih.gov/pubmed/29344291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.21560
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