Long noncoding RNA H19 derived miR-675 regulates cell proliferation by down-regulating E2F-1 in human pancreatic ductal adenocarcinoma

The long noncoding RNA (lncRNA) H19 has been proven to be overexpressed in human pancreatic ductal adenocarcinoma (PDAC). H19-induced PDAC cell proliferation is cell cycle-dependent by modulating E2F-1. However, the mechanism of how H19 regulates E2F-1 remains unclear. In this study, we investigated...

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Veröffentlicht in:J Cancer
Hauptverfasser: Ma, Ling, Tian, Xiaodong, Guo, Huahu, Zhang, Zhengkui, Du, Chong, Wang, Feng, Xie, Xuehai, Gao, Hongqiao, Zhuang, Yan, Kornmann, Marko, Gao, Hong, Yang, Yinmo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771346/
https://ncbi.nlm.nih.gov/pubmed/29344285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.21347
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