Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells

The present study investigated whether antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes can enhance the killing effect of CD8(+) cytotoxic T lymphocytes (CTLs) on lung stem-like cancer cells (SLCCs). The CTLs were generated using an accelerated co-cultured dendriti...

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Publicado en:J Cancer
Autores principales: Zhang, Xueyan, Zhang, Yanwei, Xu, Jianlin, Wang, Huimin, Zheng, Xiaoxuan, Lou, Yuqing, Han, Baohui
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2018
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771344/
https://ncbi.nlm.nih.gov/pubmed/29344283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.20821
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