Akt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesis

Epidermal growth factor receptor (EGFR) is a key oncogene in lung adenocarcinoma (LUAD). Resistance to EGFR tyrosine kinase inhibitors is a major obstacle for EGFR-mutant LUAD patients. Our gene chip array, quantitative polymerase chain reaction validation, and shRNA-based high-content screening ide...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lou, Yuqing, Xu, Jianlin, Zhang, Yanwei, Zhang, Wei, Zhang, Xueyan, Gu, Ping, Zhong, Hua, Wang, Huimin, Lu, Jun, Han, Baohui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876134/
https://ncbi.nlm.nih.gov/pubmed/33568630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03439-8
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