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Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy

GABA-A receptors play a pivotal role in many brain diseases. Epilepsy is caused by acquired conditions and genetic defects in GABA receptor channels regulating neuronal excitability in the brain. The latter is referred to as GABA channelopathies. In the last two decades, major advances have been mad...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Chuang, Shu-Hui, Reddy, Doodipala Samba
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771312/
https://ncbi.nlm.nih.gov/pubmed/29142081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.244673
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