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p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications

BACKGROUND: The risk of diabetic complications is modified by genetic and epigenetic factors. p66Shc drives the hyperglycaemic cell damage and its deletion prevents experimental diabetic complications. We herein tested whether p66Shc expression in peripheral blood mononuclear cells (PBMCs) predicts...

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Détails bibliographiques
Publié dans:Cardiovasc Diabetol
Auteurs principaux: Fadini, Gian Paolo, Albiero, Mattia, Bonora, Benedetta Maria, Poncina, Nicol, Vigili de Kreutzenberg, Saula, Avogaro, Angelo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771224/
https://ncbi.nlm.nih.gov/pubmed/29343271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-018-0660-9
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