FineMAV: prioritizing candidate genetic variants driving local adaptations in human populations

We present a new method, Fine-Mapping of Adaptive Variation (FineMAV), which combines population differentiation, derived allele frequency, and molecular functionality to prioritize positively selected candidate variants for functional follow-up. We calibrate and test FineMAV using eight experimenta...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Szpak, Michał, Mezzavilla, Massimo, Ayub, Qasim, Chen, Yuan, Xue, Yali, Tyler-Smith, Chris
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771147/
https://ncbi.nlm.nih.gov/pubmed/29343290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1380-2
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