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Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants
Corneal resistance factor (CRF) is altered during corneal diseases progression. Genome-wide-association studies (GWAS) indicated potential CRF and disease genetics overlap. Here, we characterise 135 CRF loci following GWAS in 76029 UK Biobank participants. Enrichment of extra-cellular matrix gene-se...
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| Publicado no: | Commun Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7732848/ https://ncbi.nlm.nih.gov/pubmed/33311554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01497-w |
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