Force Spectroscopy with 9-μs Resolution and Sub-pN Stability by Tailoring AFM Cantilever Geometry

Atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS) is a powerful yet accessible means to characterize the unfolding/refolding dynamics of individual molecules and resolve closely spaced, transiently occupied folding intermediates. On a modern commercial AFM, these applicat...

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Publicat a:Biophys J
Autors principals: Edwards, Devin T., Faulk, Jaevyn K., LeBlanc, Marc-André, Perkins, Thomas T.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
Matèries:
Biophysical Letters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770970/
https://ncbi.nlm.nih.gov/pubmed/29132641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.023
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