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Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with synaptic dysfunction, pathological accumulation of β‐amyloid (Aβ), and neuronal loss. The self‐association of Aβ monomers into soluble oligomers seems to be crucial for the development of neurotoxicity (J. Neur...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Zimbone, Stefania, Monaco, Irene, Gianì, Fiorenza, Pandini, Giuseppe, Copani, Agata G., Giuffrida, Maria Laura, Rizzarelli, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770784/
https://ncbi.nlm.nih.gov/pubmed/29094448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12684
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