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Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with synaptic dysfunction, pathological accumulation of β‐amyloid (Aβ), and neuronal loss. The self‐association of Aβ monomers into soluble oligomers seems to be crucial for the development of neurotoxicity (J. Neur...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Zimbone, Stefania, Monaco, Irene, Gianì, Fiorenza, Pandini, Giuseppe, Copani, Agata G., Giuffrida, Maria Laura, Rizzarelli, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770784/
https://ncbi.nlm.nih.gov/pubmed/29094448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12684
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