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The Role of Ferroptosis in Cancer Development and Treatment Response
Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell death, which is a distinct regulated cell death comparing to other cell death. The lethal metabolic imbalance resulted from GSH depletion or inactivation of glutathione peroxidase 4 is the executor of ferropto...
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Publicado no: | Front Pharmacol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5770584/ https://ncbi.nlm.nih.gov/pubmed/29375387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00992 |
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