Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development

Human antigen R (ELAVL1; HuR) is perhaps the best-characterized RNA-binding protein. Through its overexpression in various tumor types, HuR promotes posttranscriptional regulation of target genes in multiple core signaling pathways associated with tumor progression. The role of HuR overexpression in...

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Udgivet i:Mol Cell Biol
Main Authors: Peng, Weidan, Furuuchi, Narumi, Aslanukova, Ludmila, Huang, Yu-Hung, Brown, Samantha Z., Jiang, Wei, Addya, Sankar, Vishwakarma, Vikalp, Peters, Erika, Brody, Jonathan R., Dixon, Dan A., Sawicki, Janet A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770537/
https://ncbi.nlm.nih.gov/pubmed/29133460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00427-17
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