Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development

Human antigen R (ELAVL1; HuR) is perhaps the best-characterized RNA-binding protein. Through its overexpression in various tumor types, HuR promotes posttranscriptional regulation of target genes in multiple core signaling pathways associated with tumor progression. The role of HuR overexpression in...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Peng, Weidan, Furuuchi, Narumi, Aslanukova, Ludmila, Huang, Yu-Hung, Brown, Samantha Z., Jiang, Wei, Addya, Sankar, Vishwakarma, Vikalp, Peters, Erika, Brody, Jonathan R., Dixon, Dan A., Sawicki, Janet A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770537/
https://ncbi.nlm.nih.gov/pubmed/29133460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00427-17
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