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CLOCKΔ19 mutation modifies the manner of synchrony among oscillation neurons in the suprachiasmatic nucleus

In mammals, the principal circadian oscillator exists in the hypothalamic suprachiasmatic nucleus (SCN). In the SCN, CLOCK works as an essential component of molecular circadian oscillation, and ClockΔ19 mutant mice show unique characteristics of circadian rhythms such as extended free running perio...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Sujino, Mitsugu, Asakawa, Takeshi, Nagano, Mamoru, Koinuma, Satoshi, Masumoto, Koh-Hei, Shigeyoshi, Yasufumi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770461/
https://ncbi.nlm.nih.gov/pubmed/29339832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19224-1
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