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Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition
Defining the suppressive mechanisms used by regulatory T (Treg) cells is critical for the development of effective strategies for treating tumors and chronic infections. The molecular processes that occur in responder T cells that are suppressed by Treg cells are unclear. Here we show that human Tre...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5770447/ https://ncbi.nlm.nih.gov/pubmed/29339767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02689-5 |
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