Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α

The dynamic architecture of chromatin fibers, a key determinant of genome regulation, is poorly understood. Here, we employ multimodal single-molecule Förster resonance energy transfer studies to reveal structural states and their interconversion kinetics in chromatin fibers. We show that nucleosome...

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Publicado en:Nat Commun
Autores principales: Kilic, Sinan, Felekyan, Suren, Doroshenko, Olga, Boichenko, Iuliia, Dimura, Mykola, Vardanyan, Hayk, Bryan, Louise C., Arya, Gaurav, Seidel, Claus A. M., Fierz, Beat
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770380/
https://ncbi.nlm.nih.gov/pubmed/29339721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02619-5
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