MicroRNA-145 Increases the Apoptosis of Activated Hepatic Stellate Cells Induced by TRAIL through NF-κB Signaling Pathway

During the liver fibrosis recovery stage tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can effectively induce apoptosis of activated hepatic stellate cells (HSCs). Normal hepatic stellate cells are resistant to TRAIL cytotoxicity. Therefore, enhancing the sensitivity of TRAIL-induc...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Yang, Junfa, Liu, Qingxue, Cao, Shiyang, Xu, Tao, Li, Xiaofeng, Zhou, Dandan, Pan, Linxin, Li, Changyao, Huang, Cheng, Meng, Xiaoming, Zhang, Lei, Wang, Xiao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770373/
https://ncbi.nlm.nih.gov/pubmed/29375381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00980
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