TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis

The TRAIL pathway can mediate apoptosis of hepatic stellate cells to promote the resolution of liver fibrosis. However, TRAIL has the capacity to bind to regulatory receptors in addition to death-inducing receptors; their differential roles in liver fibrosis have not been investigated. Here we have...

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Publicado no:Sci Rep
Main Authors: Singh, Harsimran D., Otano, Itziar, Rombouts, Krista, Singh, Kasha P., Peppa, Dimitra, Gill, Upkar S., Böttcher, Katrin, Kennedy, Patrick T. F., Oben, Jude, Pinzani, Massimo, Walczak, Henning, Fusai, Giuseppe, Rosenberg, William M. C., Maini, Mala K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514093/
https://ncbi.nlm.nih.gov/pubmed/28717244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05845-5
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