Stable Isotope Pharmacokinetic Studies Provide Insight into Effects of Age, Sex, and Weight on Levothyroxine Metabolism

Background: This study sought to determine whether levothyroxine pharmacokinetics (PKs) are affected by age, weight, and sex. Methods: A PK study was performed after administration of a tracer dose of carbon-13-labeled LT4 ((13)C-LT4). The study was conducted at an academic medical center. Adults of...

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Udgivet i:Thyroid
Main Authors: Younis, Islam R., Ahmed, Mariam A., Burman, Kenneth D., Soldin, Offie P., Jonklaas, Jacqueline
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2018
Fag:
Original StudiesThyroid Dysfunction: Hypothyroidism, Thyrotoxicosis, and Thyroid Function Tests
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770123/
https://ncbi.nlm.nih.gov/pubmed/29212434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2017.0380
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