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Identifying drug-pathway association pairs based on L(2,1)-integrative penalized matrix decomposition

BACKGROUND: Traditional drug identification methods follow the “one drug-one target” thought. But those methods ignore the natural characters of human diseases. To overcome this limitation, many identification methods of drug-pathway association pairs have been developed, such as the integrative pen...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Liu, Jin-Xing, Wang, Dong-Qin, Zheng, Chun-Hou, Gao, Ying-Lian, Wu, Sha-Sha, Shang, Jun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770056/
https://ncbi.nlm.nih.gov/pubmed/29297378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0480-7
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