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Identifying drug-pathway association pairs based on L1L2,1-integrative penalized matrix decomposition
The traditional methods of drug discovery follow the “one drug-one target” approach, which ignores the cellular and physiological environment of the action mechanism of drugs. However, pathway-based drug discovery methods can overcome this limitation. This kind of method, such as the Integrative Pen...
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| Vydáno v: | Oncotarget |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564627/ https://ncbi.nlm.nih.gov/pubmed/28624800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18254 |
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