Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells

Recent studies have shown that a subset of nucleoporins (Nups) can detach from the nuclear pore complex and move into the nuclear interior to regulate transcription. One such dynamic Nup, called Nup98, has been implicated in gene activation in healthy cells and has been shown to drive leukemogenesis...

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Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Franks, Tobias M., McCloskey, Asako, Shokhirev, Maxim Nikolaievich, Benner, Chris, Rathore, Annie, Hetzer, Martin W.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769767/
https://ncbi.nlm.nih.gov/pubmed/29269482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.306753.117
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