Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells

Recent studies have shown that a subset of nucleoporins (Nups) can detach from the nuclear pore complex and move into the nuclear interior to regulate transcription. One such dynamic Nup, called Nup98, has been implicated in gene activation in healthy cells and has been shown to drive leukemogenesis...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Franks, Tobias M., McCloskey, Asako, Shokhirev, Maxim Nikolaievich, Benner, Chris, Rathore, Annie, Hetzer, Martin W.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769767/
https://ncbi.nlm.nih.gov/pubmed/29269482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.306753.117
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