ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells

PURPOSE: Uveal melanoma (UM) is uniformly refractory to all available systemic chemotherapies, thus creating an urgent need for novel therapeutics. In this study, we investigated the sensitivity of UM cells to ICG-001, a small molecule reported to suppress the Wnt/β-catenin–mediated transcriptional...

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Dettagli Bibliografici
Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Kaochar, Salma, Dong, Jianrong, Torres, Marie, Rajapakshe, Kimal, Nikolos, Fotis, Davis, Christel M., Ehli, Erik A., Coarfa, Cristian, Mitsiades, Nicholas, Poulaki, Vasiliki
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2018
Soggetti:
Anatomy and Pathology/Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769500/
https://ncbi.nlm.nih.gov/pubmed/29332125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22454
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