ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells

PURPOSE: Uveal melanoma (UM) is uniformly refractory to all available systemic chemotherapies, thus creating an urgent need for novel therapeutics. In this study, we investigated the sensitivity of UM cells to ICG-001, a small molecule reported to suppress the Wnt/β-catenin–mediated transcriptional...

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Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Kaochar, Salma, Dong, Jianrong, Torres, Marie, Rajapakshe, Kimal, Nikolos, Fotis, Davis, Christel M., Ehli, Erik A., Coarfa, Cristian, Mitsiades, Nicholas, Poulaki, Vasiliki
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2018
Предметы:
Anatomy and Pathology/Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769500/
https://ncbi.nlm.nih.gov/pubmed/29332125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22454
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