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Efficacy of a ketogenic diet with concomitant intranasal perillyl alcohol as a novel strategy for the therapy of recurrent glioblastoma

It has been hypothesized that persistent ketotic hypoglycemia represents a potential therapeutic strategy against high-grade gliomas. Perillyl alcohol (POH) is a non-toxic, naturally-occurring, hydroxylated monoterpene that exhibits cytotoxicity against temozolomide-resistant glioma cells, regardles...

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Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Santos, Juliana Guimarães, Da Cruz, Wanise Maria Souza, Schönthal, Axel H., Salazar, Marcela D'alincourt, Fontes, Cristina Asvolinsque Pantaleão, Quirico-Santos, Thereza, Da Fonseca, Clovis Orlando
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769394/
https://ncbi.nlm.nih.gov/pubmed/29391903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7362
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