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Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice
Huntington's disease (HD) is an inherited neurodegenerative disorder with no disease-modifying treatment. Expansion of the glutamine-encoding repeat in the Huntingtin (HTT) gene causes broad effects that are a challenge for single treatment strategies. Strategies based on human stem cells offer...
שמור ב:
| הוצא לאור ב: | Stem Cell Reports |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5768890/ https://ncbi.nlm.nih.gov/pubmed/29233555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.11.005 |
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