Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen

Whether hematopoietic cell-restricted distribution of antigens affects the degree of thymic negative selection has not been investigated in detail. Here, we show that T cells specific for hematopoietic cell-restricted antigens (HRA) are not completely deleted in the thymus, using the mouse minor his...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ju, Ji-Min, Jung, Min Ho, Nam, Giri, Kim, Woojin, Oh, Sehwa, Kim, Hyun Duk, Kim, Joo Young, Chang, Jun, Lee, Sung Hak, Park, Gyeong Sin, Min, Chang-Ki, Lee, Dong-Sup, Kim, Moon Gyo, Choi, Kyungho, Choi, Eun Young
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768767/
https://ncbi.nlm.nih.gov/pubmed/29335408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02665-z
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