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Monitoring single-cell gene regulation under dynamically controllable conditions with integrated microfluidics and software

Much is still not understood about how gene regulatory interactions control cell fate decisions in single cells, in part due to the difficulty of directly observing gene regulatory processes in vivo. We introduce here a novel integrated setup consisting of a microfluidic chip and accompanying analys...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kaiser, Matthias, Jug, Florian, Julou, Thomas, Deshpande, Siddharth, Pfohl, Thomas, Silander, Olin K., Myers, Gene, van Nimwegen, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768764/
https://ncbi.nlm.nih.gov/pubmed/29335514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02505-0
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