Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

The communication between tumor-derived elements and stroma in the metastatic niche has a critical role in facilitating cancer metastasis. Yet, the mechanisms tumor cells use to control metastatic niche formation are not fully understood. Here we report that in the lung metastatic niche, high-metast...

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Udgivet i:Nat Commun
Main Authors: Fang, Tian, Lv, Hongwei, Lv, Guishuai, Li, Ting, Wang, Changzheng, Han, Qin, Yu, Lexing, Su, Bo, Guo, Linna, Huang, Shanna, Cao, Dan, Tang, Liang, Tang, Shanhua, Wu, Mengchao, Yang, Wen, Wang, Hongyang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768693/
https://ncbi.nlm.nih.gov/pubmed/29335551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02583-0
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