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T cell protein tyrosine phosphatase prevents STAT1 induction of claudin-2 expression in intestinal epithelial cells
T cell protein tyrosine phosphatase (TCPTP) dephosphorylates a number of substrates, including JAK–STAT signaling proteins, which are activated by interferon (IFN)-γ, a major proinflammatory cytokine involved in conditions such as inflammatory bowel disease (IBD). A critical function of the intestin...
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| Publicado no: | Ann N Y Acad Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5768570/ https://ncbi.nlm.nih.gov/pubmed/28804910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13439 |
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