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Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2

Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) has been identified as an inflammatory bowel disease (IBD) candidate gene. However, the mechanism through which mutations in the PTPN2 gene contribute to the pathogenesis of IBD has not been identified. PTPN2 acts as a negative regulator of sig...

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Bibliografske podrobnosti
izdano v:Ann N Y Acad Sci
Glavni avtor: McCole, Declan F.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768569/
https://ncbi.nlm.nih.gov/pubmed/22671596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06522.x
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